FLRT3

Across TCGA cell cohorts, FLRT3 mutation is significantly associated with the RNA expression of many other genes, with 570 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FLRT3-associated genes across cancer lineages are OR2W3, CBY1, and JOSD1. Each is linked with FLRT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLRT3-to-partner and partner-to-FLRT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2W3 grouped by FLRT3-low versus FLRT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLRT3→partner) and Y-score (partner→FLRT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR2W3 →	+0.616	+3.577	.008	.002	3	2
LARGE_INTESTINE	CBY1 →	+0.831	+3.330	<.001	.002	3	1
LARGE_INTESTINE	JOSD1 →	+0.682	+3.364	<.001	.002	3	1
LARGE_INTESTINE	TRIP11 →	+0.693	+3.364	<.001	.002	3	1
LARGE_INTESTINE	PRX →	+0.554	+3.364	<.001	.002	3	1
LARGE_INTESTINE	SH3GL2 →	+1.039	+3.667	.003	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 570 associations by consensus.

OR2W3 by FLRT3 expression — LARGE_INTESTINE

Explore this box plot interactively →