Across TCGA pan-cancer cohorts, FLRT2 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated FLRT2 data layer compared with 24 for mass-spec protein and 10 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher FLRT2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated FLRT2 expression acts as an unfavorable survival marker, although some lineages such as OV and HNSC show a favorable association.

OV, LSCC, and HNSC are the cancer types where FLRT2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	All	1.000	0.552	.040	4	view →
LSCC	DFS	Quartile	All	0.444	1.000	.013	4	view →
HNSC	DFS	Median	All	0.741	0.540	.007	3	view →
CCRCC	OS	Median	All	0.770	1.000	.030	3	view →
LUAD	OS	Quartile	All	0.471	0.843	.015	2	view →
UCEC	DFS	Tertile	All	0.827	1.000	.046	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

Exploration

Same gene, other analysis: FLRT2 tumor-vs-normal RNA expression · all FLRT2 data types