Across TCGA patient cohorts, FLRT2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,089 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible FLRT2-associated genes across cancer lineages are VEGFC, DARS2, and NEK2. Each is linked with FLRT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLRT2-to-partner and partner-to-FLRT2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLRT2→partner) and Y-score (partner→FLRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	VEGFC →	+1.131	+0.441	<.001	<.001	3	4
HNSC	DARS2 →	-0.644	-0.469	.001	<.001	3	3
HNSC	NEK2 →	-1.030	-0.450	<.001	.001	3	3
BRCA	BRCA1 →	-0.692	-1.322	.002	.002	2	4
HNSC	INHBA →	+1.287	+0.556	<.001	<.001	3	3
GBM	NUF2 →	-1.038	-0.334	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,089 associations by consensus.

Exploration

FLRT2 survival (RNA) · tumor vs normal (RNA) · all FLRT2 data types