Across TCGA cell cohorts, FLRT2 mutation is significantly associated with the RNA expression of many other genes, with 115 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FLRT2-associated genes across cancer lineages are OR13G1, GOLGA6L6, and MT1B. Each is linked with FLRT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLRT2-to-partner and partner-to-FLRT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLRT2→partner) and Y-score (partner→FLRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR13G1 →	+0.009	+2.540	.001	.007	3	2
LUNG_NSCLC_LUSC	GOLGA6L6 →	+0.064	+4.108	.006	.005	3	1
SOFT_TISSUE	MT1B →	+0.122	+4.930	<.001	.008	3	1
SOFT_TISSUE	OR56B1 →	+0.016	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR6C6 →	+0.833	+5.977	<.001	.001	3	1
SOFT_TISSUE	OR1C1 →	+0.105	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 115 associations by consensus.

Exploration

FLRT2 survival (RNA) · tumor vs normal (RNA) · all FLRT2 data types