FLRT2

mutation — cross-omics
Cross-omicsMUTATION → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FLRT2 mutation is significantly associated with the mutation status of many other genes, with 2,084 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FLRT2-associated genes across cancer lineages are AMBRA1, DNAH1, and SACS. Each is linked with FLRT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLRT2-to-partner and partner-to-FLRT2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLRT2→partner) and Y-score (partner→FLRT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCAMBRA1 →+4.263+4.263.001.00114
LUNG_NSCLC_LUSCDNAH1 →+4.263+4.263.001.00114
LUNG_NSCLC_LUSCSACS →+2.678+3.652.006.00614
SOFT_TISSUEDSP →+4.307+4.307.001.00114
LARGE_INTESTINEDOCK3 →+1.413+1.939.008.00814
BLOOD_LeukemiaPIK3CG →+3.390+5.080<.001<.00114
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,084 associations by consensus.

Exploration