FLOT2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, FLOT2 protein abundance is significantly associated with the RNA expression of many other genes, with 5,051 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FLOT2-associated genes across cancer lineages are KIAA0100, PIGS, and SLC25A4. Each is linked with FLOT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLOT2-to-partner and partner-to-FLOT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLOT2 versus KIAA0100 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLOT2→partner) and Y-score (partner→FLOT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAKIAA0100 →+0.580+0.412<.001<.00134
BRCAPIGS →+0.632+0.455<.001<.00134
CCRCCSLC25A4 →+0.544+0.265.002.00533
UCECFPR3 →-0.805-0.406.008.00233
GBMCOL5A2 →-0.903-0.201.001.00833
BRCATRAF4 →+0.616+0.400<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,051 associations by consensus.

FLOT2 vs KIAA0100 — BRCA

Per-sample scatter of FLOT2 vs KIAA0100 in BRCA (Pearson r = 0.56).

Explore this scatter interactively →

Exploration