FLOT2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FLOT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,512 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FLOT2-associated GO terms across cancer lineages are Lipoprotein localization, Protein localization to plasma membrane raft, and Methylglyoxal catabolic process. Each is linked with FLOT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both FLOT2-to-partner and partner-to-FLOT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lipoprotein localization grouped by FLOT2-low versus FLOT2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLOT2→partner) and Y-score (partner→FLOT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARYLipoprotein localization →+0.156+0.742<.001<.001312
KIDNEYProtein localization to plasma membrane raft →+0.210+0.939.001.004311
SOFT_TISSUEMethylglyoxal catabolic process →+0.115+1.020.002.003311
STOMACHRegulation of transcription initiation by RNA polymerase II →+0.064+1.243.001.003311
UPPER_AERODIGESTIVE_TRACTEpigenetic regulation of gene expression →+0.057+1.720<.001<.001311
UPPER_AERODIGESTIVE_TRACTNegative regulation of mRNA splicing, via spliceosome →+0.129+1.355<.001<.001311
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,512 associations by consensus.

Lipoprotein localization by FLOT2 expression — OVARY

Box plot of Lipoprotein localization in FLOT2-low vs FLOT2-high samples in OVARY.

Explore this box plot interactively →

Exploration