FLNB-AS1

Across TCGA pan-cancer cohorts, FLNB-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated FLNB-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher FLNB-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FLNB-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

MESO, CESC, and UCS are the cancer types where FLNB-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	OS	Median	All	0.253	0.500	<.001	120	view →
CESC	OS	Tertile	All	0.466	0.767	<.001	80	view →
UCS	DFS	Median	IV	0.952	0.367	.001	58	view →
BRCA	OS	Tertile	III,IV	0.962	0.831	<.001	54	view →
UVM	OS	Quartile	III,IV	0.335	1.000	<.001	44	view →
ESCA	DFS	Median	All	0.624	0.429	.002	41	view →
READ	OS	Quartile	All	0.969	0.334	<.001	39	view →
SKCM	DFS	Quartile	III,IV	0.647	0.445	.009	25	view →
LUSC	DFS	Tertile	All	0.701	0.884	.010	16	view →
PRAD	DFS	Quartile	All	0.891	0.953	.007	14	view →
COAD	DFS	Median	All	0.598	0.769	.007	13	view →
PCPG	DFS	Median	All	0.702	0.958	.015	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

FLNB-AS1–MESO (OS)

Open the MESO breakdown →