FLII

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FLII RNA expression is significantly associated with the go_rna of many other GO terms, with 4,854 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FLII-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Regulation of nucleocytoplasmic transport. Each is linked with FLII in more than 13 cancer types. Because this analysis shows association rather than direction, both FLII-to-partner and partner-to-FLII results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by FLII-low versus FLII-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLII→partner) and Y-score (partner→FLII) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEEndosomal transport →+0.081+1.605<.001<.001314
BONECytosolic transport →+0.081+1.230.001.002313
BONERegulation of nucleocytoplasmic transport →+0.081+1.760<.001<.001313
LARGE_INTESTINERetrograde transport, endosome to Golgi →+0.055+0.948.001.001313
BONEProtein depolymerization →+0.124+1.671<.001<.001312
BONEAssembly of actomyosin apparatus involved in cytokinesis →+0.175+1.146<.001<.001312
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,854 associations by consensus.

Endosomal transport by FLII expression — BONE

Box plot of Endosomal transport in FLII-low vs FLII-high samples in BONE.

Explore this box plot interactively →

Exploration