FLI1

Across TCGA patient cohorts, FLI1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,255 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FLI1-associated genes across cancer lineages are CSF2RB, RASAL3, and GZMK. Each is linked with FLI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FLI1-to-partner and partner-to-FLI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLI1 versus CSF2RB in LSCC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLI1→partner) and Y-score (partner→FLI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CSF2RB →	+1.170	+0.559	<.001	<.001	3	8
LSCC	RASAL3 →	+0.953	+0.507	<.001	<.001	3	8
OV	GZMK →	+1.466	+0.800	.002	.002	3	8
LSCC	TNFRSF8 →	+0.633	+0.426	<.001	<.001	3	8
HNSC	GMFG →	+1.088	+0.357	<.001	<.001	3	8
UCEC	GIMAP6 →	+1.040	+0.445	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,255 associations by consensus.

FLI1 vs CSF2RB — LSCC

Explore this scatter interactively →