FLI1

Across TCGA patient cohorts, FLI1 protein abundance is significantly associated with the protein abundance of many other proteins, with 23,624 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FLI1-associated proteins across cancer lineages are ARHGAP25, ARHGDIB, and RCSD1. Each is linked with FLI1 in more than 7 cancer types. Because this analysis shows association rather than direction, both FLI1-to-partner and partner-to-FLI1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FLI1 versus ARHGAP25 in LSCC, with a Pearson correlation of 0.92.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FLI1→partner) and Y-score (partner→FLI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARHGAP25 →	+0.737	+0.620	<.001	<.001	3	8
LSCC	ARHGDIB →	+0.754	+0.592	<.001	<.001	3	8
LSCC	RCSD1 →	+0.769	+0.623	<.001	<.001	3	8
OV	SEPTIN1 →	+1.687	+1.435	.004	.006	3	8
UCEC	SKAP2 →	+0.645	+0.400	<.001	<.001	3	8
OV	WAS →	+0.623	+0.973	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,624 associations by consensus.

FLI1 vs ARHGAP25 — LSCC

Explore this scatter interactively →