FLI1

Across TCGA cell cohorts, FLI1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,385 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FLI1-associated GO terms across cancer lineages are Regulation of intracellular protein transport, Peptidyl-lysine oxidation, and Substrate adhesion-dependent cell spreading. Each is linked with FLI1 in more than 10 cancer types. Because this analysis shows association rather than direction, both FLI1-to-partner and partner-to-FLI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of intracellular protein transport grouped by FLI1-low versus FLI1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FLI1→partner) and Y-score (partner→FLI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of intracellular protein transport →	+0.066	+1.696	.001	<.001	3	11
BREAST	Peptidyl-lysine oxidation →	+1.191	+0.671	<.001	<.001	3	9
SOFT_TISSUE	Substrate adhesion-dependent cell spreading →	+0.185	+2.064	<.001	<.001	3	9
BLOOD_Leukemia	Regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway →	+0.134	+1.232	<.001	<.001	3	9
SOFT_TISSUE	Cellular response to environmental stimulus →	+0.036	+1.616	<.001	<.001	3	8
LIVER	Regulation of plasminogen activation →	+0.302	+2.491	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,385 associations by consensus.

Regulation of intracellular protein transport by FLI1 expression — SKIN

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