FLG-AS1

Across TCGA pan-cancer cohorts, FLG-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated FLG-AS1 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher FLG-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated FLG-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and UCS show a favorable association.

OV, STAD, and CHOL are the cancer types where FLG-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Tertile	IV	0.290	0.611	.003	70	view →
STAD	OS	Tertile	All	0.444	0.665	.006	47	view →
CHOL	DFS	Median	All	0.196	0.636	<.001	47	view →
KIRC	DFS	Tertile	II,III,IV	0.415	0.637	.003	40	view →
LGG	OS	Median	All	0.513	0.390	<.001	34	view →
UCS	DFS	Tertile	III,IV	0.629	0.229	.010	26	view →
UCEC	DFS	Tertile	All	0.762	0.869	.001	26	view →
SKCM	OS	Tertile	All	0.293	0.441	.005	22	view →
UVM	OS	Tertile	II,III,IV	0.934	0.609	.015	12	view →
GBM	DFS	Quartile	All	0.169	0.346	.010	9	view →
SARC	DFS	Tertile	All	0.697	0.535	.004	8	view →
ESCA	OS	Tertile	All	1.000	0.407	.017	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

FLG-AS1–OV (DFS)

Open the OV breakdown →