FLAD1

Across TCGA patient cohorts, FLAD1 mutation is significantly associated with the immune_cell of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FLAD1-associated genes across cancer lineages are Erythrocytes, Th2 cells, and CD8+ naive T-cells. Each is linked with FLAD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both FLAD1-to-partner and partner-to-FLAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Erythrocytes grouped by FLAD1-low versus FLAD1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLAD1→partner) and Y-score (partner→FLAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Erythrocytes →	+0.026	+2.432	.001	.015	3	4
UCEC	Th2 cells →	+0.187	+2.470	.004	.010	3	3
UCEC	CD8+ naive T-cells →	+0.032	+1.906	.001	.029	3	3
SKCM	Myocytes →	+0.060	+3.064	<.001	.016	3	2
SKCM	Th1 cells →	-0.115	-2.312	.001	.034	2	2
STAD	GMP →	+0.091	+2.584	.003	.036	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Erythrocytes by FLAD1 expression — SKCM

Explore this box plot interactively →