FLAD1

Across TCGA cell cohorts, FLAD1 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FLAD1-associated genes across cancer lineages are SLC6A1, OR13C7, and BTBD16. Each is linked with FLAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both FLAD1-to-partner and partner-to-FLAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC6A1 grouped by FLAD1-low versus FLAD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FLAD1→partner) and Y-score (partner→FLAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	SLC6A1 →	+0.043	+3.289	<.001	.009	3	2
LARGE_INTESTINE	OR13C7 →	+0.016	+4.415	<.001	.007	3	1
BLOOD_Leukemia	BTBD16 →	+0.065	+3.696	.001	.006	3	1
BLOOD_Leukemia	FOXS1 →	+0.053	+3.551	.002	.008	3	1
BLOOD_Leukemia	SRY →	+0.018	+3.289	.005	.009	3	1
BLOOD_Leukemia	MC2R →	+0.003	+3.969	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SLC6A1 by FLAD1 expression — BLOOD_Leukemia

Explore this box plot interactively →