FKTN

Across TCGA cell cohorts, FKTN mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible FKTN-associated genes across cancer lineages are IFNA6, FAM71B, and NAT8B. Each is linked with FKTN in more than 1 cancer types. Because this analysis shows association rather than direction, both FKTN-to-partner and partner-to-FKTN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA6 grouped by FKTN-low versus FKTN-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKTN→partner) and Y-score (partner→FKTN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFNA6 →	+0.120	+5.781	<.001	.001	3	1
LUNG_NSCLC_LUAD	FAM71B →	+0.004	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	NAT8B →	+0.071	+4.371	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

IFNA6 by FKTN expression — BREAST

Explore this box plot interactively →