FKRP

Across TCGA patient cohorts, FKRP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,462 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FKRP-associated proteins across cancer lineages are SAE1, HERC4, and IRF2BP1. Each is linked with FKRP in more than 6 cancer types. Because this analysis shows association rather than direction, both FKRP-to-partner and partner-to-FKRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKRP versus SAE1 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FKRP→partner) and Y-score (partner→FKRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAE1 →	+0.349	+0.335	<.001	.001	3	7
HNSC	HERC4 →	-0.148	-0.289	<.001	.002	3	5
HNSC	IRF2BP1 →	+0.291	+0.391	<.001	.003	3	5
COAD	PRMT1 →	+0.324	+0.399	<.001	<.001	3	5
OV	STRN4 →	+0.199	+0.452	.002	.001	2	6
CCRCC	RIPK2 →	-0.299	-0.388	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,462 associations by consensus.

FKRP vs SAE1 — GBM

Explore this scatter interactively →