FKRP

Across TCGA patient cohorts, FKRP protein abundance is significantly associated with the RNA expression of many other genes, with 747 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FKRP-associated genes across cancer lineages are SCP2D1-AS1, VSIR, and CLEC10A. Each is linked with FKRP in more than 1 cancer types. Because this analysis shows association rather than direction, both FKRP-to-partner and partner-to-FKRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKRP versus SCP2D1-AS1 in UCEC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKRP→partner) and Y-score (partner→FKRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SCP2D1-AS1 →	+0.380	+0.533	<.001	.006	3	2
UCEC	VSIR →	+1.217	+0.501	.001	.009	3	1
UCEC	CLEC10A →	+1.553	+0.501	<.001	.009	3	1
UCEC	RAB37 →	+0.529	+0.501	.001	.009	3	1
UCEC	TCERG1L →	+0.069	+0.605	.007	.003	3	1
UCEC	CXCR2 →	+1.244	+0.501	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 747 associations by consensus.

FKRP vs SCP2D1-AS1 — UCEC

Explore this scatter interactively →