FKRP

Across TCGA patient cohorts, FKRP protein abundance is significantly associated with the protein abundance of many other proteins, with 2,841 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FKRP-associated proteins across cancer lineages are TJP1_S277, ACAD11_T361, and CLIP1_S312. Each is linked with FKRP in more than 1 cancer types. Because this analysis shows association rather than direction, both FKRP-to-partner and partner-to-FKRP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKRP versus TJP1_S277 in HNSC, with a Pearson correlation of 0.73.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FKRP→partner) and Y-score (partner→FKRP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TJP1_S277 →	+0.736	+0.839	<.001	<.001	3	2
CCRCC	ACAD11_T361 →	+0.703	+0.412	<.001	<.001	3	1
CCRCC	CLIP1_S312 →	+0.424	+0.516	<.001	.001	3	1
CCRCC	DMTN_S92 →	+0.401	+0.269	.001	.002	3	1
CCRCC	EDC4_S768 →	+0.484	+0.328	.001	.001	3	1
GBM	ALDH1L1 →	+0.722	+0.358	.006	.001	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,841 associations by consensus.

FKRP vs TJP1_S277 — HNSC

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