Across TCGA pan-cancer cohorts, FKBPL Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated FKBPL data layer compared with 27 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FKBPL Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FKBPL expression acts as an unfavorable survival marker.

HNSC and GBM are the cancer types where FKBPL Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.069	0.768	<.001	24	view →
GBM	OS	Median	All	0.101	0.413	.035	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: FKBPL tumor-vs-normal RNA expression · all FKBPL data types