Across TCGA pan-cancer cohorts, FKBPL mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated FKBPL data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FKBPL mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated FKBPL expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where FKBPL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	II,III,IV	1.000	0.724	.003	67	view →
HNSC	DFS	Quartile	II,III,IV	0.796	0.516	.020	17	view →
LSCC	OS	Tertile	All	0.975	0.822	.021	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: FKBPL tumor-vs-normal RNA expression · all FKBPL data types