Across TCGA patient cohorts, FKBPL protein abundance is significantly associated with the RNA expression of many other genes, with 4,135 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible FKBPL-associated genes across cancer lineages are RNASEH2C, NELFE, and HIKESHI. Each is linked with FKBPL in more than 2 cancer types. Because this analysis shows association rather than direction, both FKBPL-to-partner and partner-to-FKBPL results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBPL→partner) and Y-score (partner→FKBPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNASEH2C →	+0.459	+0.588	.001	.008	3	3
LSCC	NELFE →	+0.710	+0.269	<.001	<.001	3	3
BRCA	HIKESHI →	+0.525	+0.249	<.001	<.001	3	3
LSCC	STK19 →	+0.537	+0.220	<.001	.001	3	3
LSCC	GPANK1 →	+0.363	+0.217	<.001	<.001	3	3
CCRCC	NFKBIL1 →	+0.361	+0.295	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,135 associations by consensus.

Exploration

FKBPL survival (RNA) · tumor vs normal (RNA) · all FKBPL data types