Across TCGA patient cohorts, FKBPL mutation is significantly associated with the RNA expression of many other genes, with 237 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBPL-associated genes across cancer lineages are LINC00709, LINC01789, and CCL18. Each is linked with FKBPL in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBPL-to-partner and partner-to-FKBPL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBPL→partner) and Y-score (partner→FKBPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC00709 →	+0.079	+7.930	<.001	.008	3	2
SKCM	LINC01789 →	+0.070	+4.324	<.001	.007	3	2
UCEC	CCL18 →	+1.647	+3.330	.003	.005	3	1
UCEC	TRBV18 →	+0.748	+3.470	.001	.003	3	1
COAD	RNA5SP442 →	+0.492	+4.893	.001	.005	3	1
COAD	RNU6-1138P →	+0.508	+4.790	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 237 associations by consensus.

Exploration

FKBPL survival (RNA) · tumor vs normal (RNA) · all FKBPL data types