FKBP9

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FKBP9 mutation is significantly associated with the drug of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FKBP9-associated genes across cancer lineages are GSK2276186C, GSK1070916, and Masitinib. Each is linked with FKBP9 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP9-to-partner and partner-to-FKBP9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2276186C grouped by FKBP9-low versus FKBP9-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP9→partner) and Y-score (partner→FKBP9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEGSK2276186C →+0.460+2.649.048.04631
LARGE_INTESTINEGSK1070916 →+0.763+2.655.009.04431
LARGE_INTESTINEMasitinib →+0.451+2.652.036.04531
LARGE_INTESTINETivozanib →+0.252+2.786.025.03731
LARGE_INTESTINEPRT062607 →+0.576+2.769.022.04021
LARGE_INTESTINEGSK2110183B →+0.676+2.649.026.04621
Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

GSK2276186C by FKBP9 expression — LARGE_INTESTINE

Box plot of GSK2276186C in FKBP9-low vs FKBP9-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration