FKBP8

Across TCGA cell cohorts, FKBP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,685 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FKBP8-associated GO terms across cancer lineages are Regulation of glycolytic process through fructose-6-phosphate, Negative regulation of glycolytic process through fructose-6-phosphate, and Energy coupled proton transmembrane transport, against electrochemical gradient. Each is linked with FKBP8 in more than 14 cancer types. Because this analysis shows association rather than direction, both FKBP8-to-partner and partner-to-FKBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of glycolytic process through fructose-6-phosphate grouped by FKBP8-low versus FKBP8-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP8→partner) and Y-score (partner→FKBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of glycolytic process through fructose-6-phosphate →	+0.159	+0.932	<.001	<.001	3	15
BREAST	Negative regulation of glycolytic process through fructose-6-phosphate →	+0.159	+0.932	<.001	<.001	3	15
URINARY_TRACT	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.090	+0.802	<.001	.004	3	13
URINARY_TRACT	Electron transport coupled proton transport →	+0.090	+0.802	<.001	.004	3	13
LUNG_NSCLC_LUSC	Positive regulation of lysosomal protein catabolic process →	+0.262	+1.234	<.001	<.001	3	13
LARGE_INTESTINE	Canonical glycolysis →	+0.102	+0.555	.003	.003	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,685 associations by consensus.

Regulation of glycolytic process through fructose-6-phosphate by FKBP8 expression — BREAST

Explore this box plot interactively →