FKBP8

Across TCGA cell cohorts, FKBP8 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. URINARY_TRACT shows the largest number of these associations.

The most reproducible FKBP8-associated genes across cancer lineages are IL3, KRTAP19-4, and OR2C3. Each is linked with FKBP8 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP8-to-partner and partner-to-FKBP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL3 grouped by FKBP8-low versus FKBP8-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP8→partner) and Y-score (partner→FKBP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	IL3 →	+0.026	+5.087	<.001	.004	3	1
URINARY_TRACT	KRTAP19-4 →	+0.193	+5.087	<.001	.004	3	1
URINARY_TRACT	OR2C3 →	+0.030	+5.087	<.001	.004	3	1
URINARY_TRACT	PABPN1L →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	KRTAP6-3 →	+0.126	+5.087	<.001	.004	3	1
KIDNEY	APCS →	+0.033	+5.000	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

IL3 by FKBP8 expression — URINARY_TRACT

Explore this box plot interactively →