FKBP7

Across TCGA pan-cancer cohorts, FKBP7 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FKBP7 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher FKBP7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FKBP7 expression acts as an unfavorable survival marker.

LSCC, UCEC, and LUAD are the cancer types where FKBP7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	DFS	Median	II,III,IV	0.493	0.855	<.001	50	view →
UCEC	OS	Quartile	II,III,IV	0.286	1.000	.003	40	view →
LUAD	DFS	Tertile	III,IV	0.412	0.968	.031	5	view →
HNSC	DFS	Median	IV	0.587	0.814	.025	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FKBP7–LSCC (DFS)

Open the LSCC breakdown →