FKBP7

Across TCGA patient cohorts, FKBP7 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP7-associated genes across cancer lineages are NDUFA12P1, OAZ1, and NME1-NME2. Each is linked with FKBP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP7-to-partner and partner-to-FKBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NDUFA12P1 grouped by FKBP7-low versus FKBP7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP7→partner) and Y-score (partner→FKBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	NDUFA12P1 →	+0.097	+5.201	<.001	.007	3	2
UCEC	OAZ1 →	+0.529	+3.245	.002	.009	3	1
UCEC	NME1-NME2 →	+0.901	+3.223	<.001	.009	3	1
UCEC	TPD52L1 →	+0.948	+3.212	.006	.009	3	1
CESC	RNU6-338P →	+0.412	+5.812	<.001	.003	3	1
CESC	MIR1827 →	+0.435	+5.306	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

NDUFA12P1 by FKBP7 expression — CESC

Explore this box plot interactively →