FKBP7

Across TCGA patient cohorts, FKBP7 mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP7-associated genes across cancer lineages are PDCD4, ATM, and Notch1. Each is linked with FKBP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both FKBP7-to-partner and partner-to-FKBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by FKBP7-low versus FKBP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP7→partner) and Y-score (partner→FKBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.605	-3.000	.026	.037	3	1
UCEC	ATM →	-0.653	-3.000	.012	.036	3	1
UCEC	Notch1 →	+0.248	+3.000	.002	.037	1	1
UCEC	STAT3_pY705 →	-0.484	-3.000	.001	.037	1	1
UCEC	Chk2 →	-0.349	-3.000	.009	.037	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PDCD4 by FKBP7 expression — UCEC

Explore this box plot interactively →