FKBP5

Across TCGA patient cohorts, FKBP5 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,830 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FKBP5-associated proteins across cancer lineages are NR3C1_T8, NR3C1_S45, and NR3C1_S211. Each is linked with FKBP5 in more than 5 cancer types. Because this analysis shows association rather than direction, both FKBP5-to-partner and partner-to-FKBP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKBP5 versus NR3C1_T8 in CCRCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP5→partner) and Y-score (partner→FKBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NR3C1_T8 →	+0.633	+2.151	<.001	<.001	3	6
LSCC	NR3C1_S45 →	+0.688	+0.763	<.001	<.001	3	5
CCRCC	NR3C1_S211 →	+1.026	+2.555	<.001	<.001	3	4
GBM	NR3C1_S267 →	+0.562	+1.537	<.001	<.001	3	4
UCEC	FERMT3 →	+0.626	+0.979	<.001	<.001	3	4
GBM	GMFG →	+0.532	+0.997	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,830 associations by consensus.

FKBP5 vs NR3C1_T8 — CCRCC

Explore this scatter interactively →