FKBP5

Across TCGA patient cohorts, FKBP5 protein abundance is significantly associated with the RNA expression of many other genes, with 12,847 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FKBP5-associated genes across cancer lineages are ARMC12, IFI30, and JAK3. Each is linked with FKBP5 in more than 6 cancer types. Because this analysis shows association rather than direction, both FKBP5-to-partner and partner-to-FKBP5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FKBP5 versus ARMC12 in BRCA, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP5→partner) and Y-score (partner→FKBP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARMC12 →	+0.597	+0.460	<.001	<.001	3	7
LSCC	IFI30 →	+0.436	+0.326	<.001	<.001	3	7
HNSC	JAK3 →	+0.675	+0.283	.001	<.001	3	6
UCEC	IL10RA →	+0.927	+0.619	<.001	.001	3	6
UCEC	ADGRE2 →	+0.746	+0.681	<.001	<.001	3	6
OV	PTPN22 →	+0.798	+0.521	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,847 associations by consensus.

FKBP5 vs ARMC12 — BRCA

Explore this scatter interactively →