FKBP3

Across TCGA pan-cancer cohorts, FKBP3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FKBP3 data layer compared with 29 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher FKBP3 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP3 expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.

HNSC, COAD, and LSCC are the cancer types where FKBP3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.242	1.000	.024	24	view →
COAD	DFS	Median	All	1.000	0.921	.015	18	view →
LSCC	OS	Median	II,III,IV	0.928	0.564	<.001	18	view →
PDAC	DFS	Median	IV	0.250	0.934	.024	6	view →
CCRCC	OS	Median	IV	1.000	0.202	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FKBP3–HNSC (OS)

Open the HNSC breakdown →