FKBP1C

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, FKBP1C RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated FKBP1C data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher FKBP1C RNA is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP1C expression acts as an unfavorable survival marker, although some lineages such as CESC and KIRC show a favorable association.

UVM, ACC, and LIHC are the cancer types where FKBP1C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSMedianAll0.3790.777.00189view →
ACCDFSQuartileAll0.2300.748<.00175view →
LIHCOSMedianAll0.6070.770<.00168view →
CESCOSTertileII,III,IV0.8920.317<.00168view →
LUADOSQuartileII,III,IV0.5580.877<.00164view →
LGGDFSMedianAll0.6540.811<.00153view →
KIRPDFSTertileAll0.8660.978<.00141view →
KIRCDFSTertileII,III,IV0.7190.498.00935view →
BRCAOSMedianIV0.3600.740.00621view →
STADOSMedianAll0.6150.825.00420view →
SKCMDFSQuartileAll0.6480.807.00319view →
THCADFSMedianAll0.8890.767.00519view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

Exploration