FKBP11

Across TCGA pan-cancer cohorts, FKBP11 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FKBP11 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher FKBP11 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated FKBP11 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where FKBP11 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.615	1.000	.001	44	view →
PDAC	DFS	Median	II,III,IV	0.656	0.800	.023	13	view →
HNSC	DFS	Median	All	0.916	0.987	.006	8	view →
LUAD	DFS	Median	III,IV	0.716	0.294	.007	7	view →
LSCC	DFS	Tertile	II,III,IV	0.621	0.896	.016	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FKBP11–CCRCC (OS)

Open the CCRCC breakdown →