FKBP11

Across TCGA cell cohorts, FKBP11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,657 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FKBP11-associated GO terms across cancer lineages are Sneeze reflex, Regulation of telomere maintenance via telomere lengthening, and Regulation of miRNA-mediated gene silencing. Each is linked with FKBP11 in more than 5 cancer types. Because this analysis shows association rather than direction, both FKBP11-to-partner and partner-to-FKBP11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sneeze reflex grouped by FKBP11-low versus FKBP11-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FKBP11→partner) and Y-score (partner→FKBP11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Sneeze reflex →	+1.706	+1.318	<.001	<.001	3	6
OVARY	Regulation of telomere maintenance via telomere lengthening →	+0.043	+1.377	.005	.003	3	5
SKIN	Regulation of miRNA-mediated gene silencing →	-0.057	-1.050	.001	<.001	3	5
SKIN	Negative regulation of gene silencing by regulatory ncRNA →	-0.142	-1.738	<.001	<.001	3	5
LARGE_INTESTINE	Nuclear receptor-mediated signaling pathway →	-0.061	-0.936	<.001	<.001	2	6
BLOOD_Leukemia	Melanosome organization →	-0.050	-0.770	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,657 associations by consensus.

Sneeze reflex by FKBP11 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →