Across TCGA patient cohorts, FITM2 mutation is significantly associated with the RNA expression of many other genes, with 931 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FITM2-associated genes across cancer lineages are RNA5SP422, COX15, and MRPL49. Each is linked with FITM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FITM2-to-partner and partner-to-FITM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FITM2→partner) and Y-score (partner→FITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP422 →	+0.600	+2.256	.008	.006	3	2
UCEC	COX15 →	+0.553	+3.329	.001	.005	3	1
UCEC	MRPL49 →	+0.593	+2.617	.003	.006	3	1
UCEC	ALDOA →	+0.562	+3.346	.006	.005	3	1
UCEC	TMCO3 →	+0.727	+3.700	.003	.001	3	1
UCEC	DLAT →	+0.688	+3.354	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 931 associations by consensus.

Exploration

FITM2 survival (RNA) · tumor vs normal (RNA) · all FITM2 data types