FITM2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, FITM2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible FITM2-associated genes across cancer lineages are CDY2A, GALP, and IFNA1. Each is linked with FITM2 in more than 1 cancer types. Because this analysis shows association rather than direction, both FITM2-to-partner and partner-to-FITM2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FITM2→partner) and Y-score (partner→FITM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaCDY2A →+0.006+6.247<.001<.00131
BLOOD_LymphomaGALP →+0.015+5.209<.001.00531
BLOOD_LymphomaIFNA1 →+0.064+4.867.005.00931
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration