FITM1

Across TCGA cell cohorts, FITM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,722 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible FITM1-associated GO terms across cancer lineages are Protein linear polyubiquitination, Myosin filament organization, and Myosin filament assembly. Each is linked with FITM1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FITM1-to-partner and partner-to-FITM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by FITM1-low versus FITM1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FITM1→partner) and Y-score (partner→FITM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Protein linear polyubiquitination →	+0.137	+0.223	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Myosin filament organization →	-0.400	-0.204	.001	<.001	3	8
LUNG_NSCLC_LUAD	Myosin filament assembly →	-0.400	-0.204	.001	<.001	3	8
BREAST	Cilium or flagellum-dependent cell motility →	-0.065	-0.181	.002	.002	2	8
BREAST	Cilium-dependent cell motility →	-0.065	-0.181	.002	.002	2	8
UPPER_AERODIGESTIVE_TRACT	Asparaginyl-tRNA aminoacylation →	-0.124	-0.181	.001	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,722 associations by consensus.

Protein linear polyubiquitination by FITM1 expression — KIDNEY

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