Across TCGA patient cohorts, FIS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,812 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FIS1-associated proteins across cancer lineages are PDAP1, EIF4H, and SLC12A9. Each is linked with FIS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FIS1-to-partner and partner-to-FIS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIS1→partner) and Y-score (partner→FIS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PDAP1 →	+0.439	+0.708	<.001	<.001	3	6
COAD	EIF4H →	+0.389	+0.687	<.001	<.001	3	5
OV	SLC12A9 →	+0.367	+0.452	<.001	.006	3	5
LSCC	ARMC10 →	+0.392	+0.546	<.001	<.001	3	5
HNSC	ZKSCAN1 →	+0.394	+0.991	<.001	.005	3	4
LUAD	BAIAP2L1 →	+0.431	+0.343	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,812 associations by consensus.

Exploration

FIS1 survival (RNA) · tumor vs normal (RNA) · all FIS1 data types