Across TCGA patient cohorts, FIS1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,628 significant associations in total. COAD shows the largest number of these associations.

The most reproducible FIS1-associated genes across cancer lineages are TMEM120A, GSTK1, and SLC12A9. Each is linked with FIS1 in more than 5 cancer types. Because this analysis shows association rather than direction, both FIS1-to-partner and partner-to-FIS1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FIS1→partner) and Y-score (partner→FIS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TMEM120A →	+0.620	+0.215	<.001	<.001	3	6
UCEC	GSTK1 →	+0.765	+0.296	<.001	<.001	3	6
HNSC	SLC12A9 →	+0.506	+0.290	<.001	<.001	3	6
HNSC	AGFG2 →	+0.780	+0.461	<.001	<.001	3	5
HNSC	ZSCAN25 →	+0.424	+0.251	<.001	<.001	3	5
HNSC	ZNHIT1 →	+0.817	+0.407	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,628 associations by consensus.

Exploration

FIS1 survival (RNA) · tumor vs normal (RNA) · all FIS1 data types