Across TCGA cell cohorts, FIS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,644 significant associations in total. CNS shows the largest number of these associations.

The most reproducible FIS1-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Regulation of mitochondrial ATP synthesis coupled proton transport. Each is linked with FIS1 in more than 8 cancer types. Because this analysis shows association rather than direction, both FIS1-to-partner and partner-to-FIS1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIS1→partner) and Y-score (partner→FIS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Peptidyl-glutamic acid carboxylation →	+0.063	+0.569	.007	.002	3	9
OVARY	Protein carboxylation →	+0.063	+0.569	.007	.002	3	9
OVARY	Regulation of mitochondrial ATP synthesis coupled proton transport →	+0.103	+0.910	<.001	<.001	3	8
CNS	Protein K27-linked deubiquitination →	-0.116	-0.880	<.001	<.001	3	8
CNS	Mitochondrial respirasome assembly →	+0.138	+0.673	<.001	<.001	3	8
LUNG_NSCLC_LUSC	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process →	-0.031	-0.797	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,644 associations by consensus.

Exploration

FIS1 survival (RNA) · tumor vs normal (RNA) · all FIS1 data types