FIP1L1

Across TCGA patient cohorts, FIP1L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,292 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible FIP1L1-associated proteins across cancer lineages are TRRAP, RTF1, and MFAP1. Each is linked with FIP1L1 in more than 4 cancer types. Because this analysis shows association rather than direction, both FIP1L1-to-partner and partner-to-FIP1L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIP1L1 versus TRRAP in HNSC, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIP1L1→partner) and Y-score (partner→FIP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRRAP →	+0.238	+0.521	<.001	.002	3	5
GBM	RTF1 →	+0.255	+0.482	.002	.002	3	5
GBM	MFAP1 →	+0.419	+0.695	<.001	.002	3	5
GBM	UBTF →	+0.411	+0.627	<.001	<.001	3	4
LSCC	USP39 →	+0.329	+0.373	<.001	<.001	3	4
GBM	RBM10 →	+0.286	+0.595	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,292 associations by consensus.

FIP1L1 vs TRRAP — HNSC

Explore this scatter interactively →