FIP1L1

Across TCGA cell cohorts, FIP1L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,017 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible FIP1L1-associated GO terms across cancer lineages are Response to dehydroepiandrosterone, Protein deubiquitination, and Transcription pausing by RNA polymerase II. Each is linked with FIP1L1 in more than 12 cancer types. Because this analysis shows association rather than direction, both FIP1L1-to-partner and partner-to-FIP1L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to dehydroepiandrosterone grouped by FIP1L1-low versus FIP1L1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FIP1L1→partner) and Y-score (partner→FIP1L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Response to dehydroepiandrosterone →	+0.121	+0.692	<.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Protein deubiquitination →	+0.052	+0.815	<.001	<.001	3	12
BLOOD_Lymphoma	Transcription pausing by RNA polymerase II →	+0.147	+0.982	<.001	<.001	3	11
SOFT_TISSUE	Cell cycle checkpoint signaling →	+0.067	+0.796	.005	.006	3	11
BREAST	Positive regulation of organelle assembly →	+0.076	+0.756	<.001	<.001	3	10
URINARY_TRACT	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.059	+0.487	.002	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,017 associations by consensus.

Response to dehydroepiandrosterone by FIP1L1 expression — BLOOD_Lymphoma

Explore this box plot interactively →