FILNC1

Across TCGA pan-cancer cohorts, FILNC1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of FILNC1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where FILNC1 RNA is repressed in tumor relative to normal tissue. In most cancer types FILNC1 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

THCA, LUAD, and KICH are the cancer types where FILNC1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in FILNC1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	−0.626	<.001	10	view →
LUAD	All	III,IV	−0.386	<.001	9	view →
KICH	Female	All	−1.525	<.001	8	view →
BRCA	Female	All	−0.318	<.001	6	view →
LUSC	Female	II,III,IV	−0.281	.004	4	view →
COAD	All	All	−0.055	.010	3	view →
KIRP	Male	All	+1.022	.026	2	view →
CHOL	All	All	+0.081	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

FILNC1–THCA

Open the THCA breakdown →