FILIP1L

Across TCGA pan-cancer cohorts, FILIP1L Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated FILIP1L data layer compared with 20 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher FILIP1L Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated FILIP1L expression acts as an unfavorable survival marker, although some lineages such as UCEC and STAD show a favorable association.

UCEC, STAD, and HNSC are the cancer types where FILIP1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	II,III,IV	0.928	0.303	.010	28	view →
STAD	DFS	Median	III,IV	1.000	0.333	.016	18	view →
HNSC	OS	Median	All	0.264	0.688	.012	6	view →
SKCM	DFS	Median	II,III,IV	0.940	0.540	.011	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

FILIP1L–UCEC (DFS)

Open the UCEC breakdown →