FILIP1L

Across TCGA pan-cancer cohorts, FILIP1L mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated FILIP1L data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher FILIP1L mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated FILIP1L expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

GBM, PDAC, and LSCC are the cancer types where FILIP1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
GBM	DFS	Tertile	All	0.259	0.527	.003	12	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LSCC	DFS	Tertile	II,III,IV	0.500	0.825	.018	3	view →
CCRCC	DFS	Quartile	III,IV	0.882	0.422	.017	2	view →
LUAD	OS	Tertile	All	0.970	0.927	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

FILIP1L–GBM (DFS)

Open the GBM breakdown →