FILIP1L

Across TCGA patient cohorts, FILIP1L mutation is significantly associated with the RNA expression of many other genes, with 5,208 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FILIP1L-associated genes across cancer lineages are TAF9, DNAJA1P1, and CCNB2. Each is linked with FILIP1L in more than 2 cancer types. Because this analysis shows association rather than direction, both FILIP1L-to-partner and partner-to-FILIP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by FILIP1L-low versus FILIP1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FILIP1L→partner) and Y-score (partner→FILIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.546	+2.192	<.001	<.001	3	3
BRCA	DNAJA1P1 →	+0.033	+5.610	.001	.004	3	3
UCEC	CCNB2 →	+0.498	+2.023	.003	.001	3	3
UCEC	RPUSD2 →	+0.324	+2.364	<.001	<.001	3	3
UCEC	LEO1 →	+0.422	+1.747	<.001	<.001	3	3
UCEC	CENPX →	+0.379	+2.102	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,208 associations by consensus.

TAF9 by FILIP1L expression — UCEC

Explore this box plot interactively →