FILIP1L

Across TCGA cell cohorts, FILIP1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,089 significant associations in total. BONE shows the largest number of these associations.

The most reproducible FILIP1L-associated GO terms across cancer lineages are Regulation of angiogenesis, Protein localization to actin cytoskeleton, and Regulation of cell junction assembly. Each is linked with FILIP1L in more than 10 cancer types. Because this analysis shows association rather than direction, both FILIP1L-to-partner and partner-to-FILIP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of angiogenesis grouped by FILIP1L-low versus FILIP1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (FILIP1L→partner) and Y-score (partner→FILIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of angiogenesis →	+0.116	+2.351	<.001	<.001	3	10
KIDNEY	Protein localization to actin cytoskeleton →	+0.175	+2.737	<.001	<.001	3	10
STOMACH	Regulation of cell junction assembly →	+0.071	+2.540	<.001	<.001	3	10
LUNG_NSCLC_LUAD	Ketone metabolic process →	-0.081	-1.182	.002	.003	3	10
BONE	Regulation of actin filament organization →	+0.065	+1.945	.002	.004	3	10
LUNG_NSCLC_LUSC	Positive regulation of immune effector process →	+0.068	+2.875	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,089 associations by consensus.

Regulation of angiogenesis by FILIP1L expression — BONE

Explore this box plot interactively →