FILIP1L

Across TCGA cell cohorts, FILIP1L mutation is significantly associated with the RNA expression of many other genes, with 1,436 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FILIP1L-associated genes across cancer lineages are EIF3L, DTWD1, and NSMCE4A. Each is linked with FILIP1L in more than 1 cancer types. Because this analysis shows association rather than direction, both FILIP1L-to-partner and partner-to-FILIP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EIF3L grouped by FILIP1L-low versus FILIP1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FILIP1L→partner) and Y-score (partner→FILIP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	EIF3L →	+0.522	+2.546	<.001	.001	3	2
LARGE_INTESTINE	DTWD1 →	+0.635	+2.949	<.001	<.001	3	2
LARGE_INTESTINE	NSMCE4A →	+0.494	+2.265	<.001	.001	3	2
LARGE_INTESTINE	UBE2D3 →	+0.463	+2.265	.001	.001	3	2
LARGE_INTESTINE	GAR1 →	+0.570	+3.459	<.001	.001	3	2
LARGE_INTESTINE	HINT3 →	+0.612	+2.265	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,436 associations by consensus.

EIF3L by FILIP1L expression — LARGE_INTESTINE

Explore this box plot interactively →