FIGN

Across TCGA patient cohorts, FIGN RNA expression is significantly associated with the protein abundance of many other proteins, with 11,537 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FIGN-associated proteins across cancer lineages are NID2, PGM1, and PHLDB1. Each is linked with FIGN in more than 4 cancer types. Because this analysis shows association rather than direction, both FIGN-to-partner and partner-to-FIGN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FIGN versus NID2 in OV, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FIGN→partner) and Y-score (partner→FIGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NID2 →	+0.545	+1.118	.001	.001	3	5
LSCC	PGM1 →	+0.558	+0.782	<.001	<.001	3	4
LSCC	PHLDB1 →	+0.479	+1.015	<.001	<.001	3	4
BRCA	CEP170 →	+0.251	+0.435	<.001	.002	3	4
OV	ETFA →	-0.518	-1.035	.001	<.001	3	4
OV	ETFB →	-0.400	-0.977	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,537 associations by consensus.

FIGN vs NID2 — OV

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